Research Areas:

• ✓ Praphulla Chandra Shukla, https://www.ncbi.nlm.nih.gov/sites/myncbi/1pC3aYNeKze5q/collections/45217560/public/, Please click the file to get all the articles
• ✓ Shukla P. C., DNA damage repair and cardiovascular diseases, Canadian Journal of Cardiology, 26, 13-16, 2010
• ✓ Singh* K. K., Shukla* P. C, Herceptin, a recombinant humanized anti-ERBB2 monoclonal antibody, induces p53-mediated cardiomyocyte death, Biochem Biophys Res Commun, 411, 421-426, 2011
• ✓ Shukla PC, Singh KK, Quan A, Al-Omran M, Teoh H, Lovren F, et.al.,, BRCA1 is an essential regulator of heart function and survival following myocardial infarction, Nature Communications, 2011
• ✓ Desjardins, J-F., Lovren, F., Pan, Y., Garg, V., Gosal, S., Garg, A., Szmitko, P.E., Schneider, M.D., BRCA2 deficiency exaggerates doxorubicin-induced cardiomyocyte apoptosis and cardiac failure, Journal of Biological Chemistry, 2012
• ✓ Quan, A., Lovren, F, Pan, Y., Wagg, C. S., Teoh, H., Lopaschuk, G. D., Verma, S., Regulating cardiac energy metabolism and bioenergetics by targeting the DNA damage repair protein BRCA1, Journal of Thoracic and Cardiovascular Surgery, 2013
• ✓ P.C., Quan, A., Al-Omran, M., Lovren, F., Pan, Y., Brezden-Masley, C., Ingram, A.J., Stanford, W.L., Teoh, H., Verma, S., BRCA1 is a Novel Target to Improve Endothelial Dysfunction and Retard Atherosclerosis, Journal of Thoracic and Cardiovascular Surgery
• ✓ Thompson, M.D., Mei, Y., Weisbrod, R.M., Silver, M., Shukla, P.C., Bolotina, V.M., Cohen, R.A., Tong, X, Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase C674 regulate endothelial cell calcium stores and angiogenic function as well as
• ✓ Loebel M, Holzhauser L, Hartwig JA, Shukla PC, Savvatis K, Jenke A, Skurk C. et.al,, The forkhead transcription factor Foxo3 negatively regulates natural killer cell function and viral clearance in myocarditis, European Heart Journal, 876-887, 2018
• ✓ Bhattacharya A, Chowdhury A, Chaudhury K, Shukla PC., Proprotein convertase subtilisin/kexin type 9 (PCSK9): A potential multifaceted player in cancer, Biochim Biophys Acta Rev Cancer., 1876, 188581, 2021
• ✓ Duddu S, Agrawal M, Chakrabarti R, Ghosh A, Chakravorty N, Tiwari A, Shukla PC., Meta-analysis reveals inhibition of the inflammatory cytokine IL-6 affords limited protection post-myocardial ischemia/infarction., Heliyon, 8(8), 2022
• ✓ Mukherjee M, Rahaman M, Ray SK, Shukla PC, Dolai TK, Chakravorty N., Revisiting fetal hemoglobin inducers in beta-hemoglobinopathies: a review of natural products, conventional and combinatorial therapies, Mol Biol Rep, 2022
• ✓ Rahaman M, Mukherjee M, Bhattacharya S, Mukherjee B, Shukla PC, Dolai TK, Chakravorty N., Exploring the crosstalk between long non-coding RNAs and microRNAs to unravel potential prognostic and therapeutic biomarkers in ?-thalassemia, Mol Biol Rep, 2022
• ✓ Rituparna Chakrabarti, Sushmitha Duddu, Ashutosh Tiwari, K. Tejaswi Naidu, Pooja Sharma, Nishant Chakravorty, Praphulla Chandra Shukla, Natural Killer T cells and the invariant subset promote atherosclerosis: A meta-analysis, Life Sciences, 321, 121620, 2

• ✓ HC Haplotypes in HBE/Beta Thalassemia: Correlating Disease Heterogeneity and Blood Transfusion Requirements in West Bengal
• ✓ MicroRNA based Reprogramming of Fetal Haemoglobin in Beta-Thalassemia
• ✓ Identification of Non-Coding RNAs Regulation MLKL/RIPK3 Pathway in Vascular Smooth Muscle Cells: Role of Novel Non-coding RNAs in VSMC Necroptosis
• ✓ Endothelial Function and Thrombotic Thrombocytopenia in SARS-CoV2
• ✓ Deubiquitinases in Endothelial Function

Awards will be updated soon.

Patents will be updated soon.