Soumen Das

Thu, 4 Dec 2025 - 06:14

mypanel

Designation

Head and Professor

Email

sou@smst.iitkgp.ac.in

BioMEMS is a rapidly advancing, inter-disciplinary research field for creation and development of new methods/systems to effectively process or manipulate biological materials with electronic devices and components. Giving a prior importance to the biomedical sensing research, an interdisciplinary R&D work at School of Medical Science and Technology, IIT Kharagpur has been initiated to promote MEMS and Biosensor activity that encompasses design, fabrication and engineering of biomedical & microfluidic devices for its electro-physiological characterisation. For the evaluation of electrical and physical properties of biomolecules and cells using suitable micro-fluidic devices, appropriate fabrication of polymeric coated bio-MEMS are being investigated and its utility are evaluated under different microscopic and electrical impedance study. The research also involves development of different BioMEMS transducers and related technologies for sensing various biomedical signals for precise and appropriate diagnostics and therapeutics. Microfabrication technology is being explored to develop various miniature MEMS devices for deployment of in-vivo and in-vitro detection of biomedical signals and its characterisation.

Presently, the following activities are being pursued:

Development of MEMS based flow sensor on flexible substrate - Realization of a polymer (PDMS) based cardiovascular shear stress/ flow sensor using micro fabrication techniques on catheter to monitor real-time blood flow for atherosclerosis diagnosis satisfying sensitivity, biocompatibility and reliability requirements. The major aim of this research is to develop catheter-based MEMS sensors to provide high spatial and temporal resolution for real-time monitoring in the vasculature.
Separation and manipulation of cells on Microfluidic Platform by Dielectrophoresis - Realization of an integrated microfluidic device with planer electrodes for rapid and continuous separation of biological cells in mixed cell population with high selectivity using dielectrophoresis technique.
MEMS based Biosensor for Electrophysiological characterization of cells – Electrical impedance spectroscopy (EIS) is used to study the electrochemical phenomena in cells and the toxicological effects in cells.

Research Areas:

Microfluidics

Sensors & Actuators

MEMS and Microsystems

Biomedical Devices, Flexible Electronics

BioMEMS

✓ Anura A., Das D. , Pal M. , Paul R. R., Das S. , Chatterjee J, Unrevealing nanomechanical signatures of epithelial and connective tissue of oral submucous fibrosis, Biophysical Society Conference: Mechanobiology of Disease, 2016
✓ Wala J., Das S., Effect of physico-mechanical properties of PDMS substrate on cell behavior, Proceeding of the Mechanobiology of Disease meeting, 2016
✓ Tripathi A. S., Chatterjee B. P., Das S, Design and Simulation of Electroactive Polymer-Based Artificial Muscles for Biomedical Application, Proceedings of the 2016 COMSOL Conference, 2016
✓ Das D., Anura A. , Das S. , Mandal M. , Das S., AFM based Biomechanical Characterization for Assessment of Cancer Aggressiveness, Biophysical Society Conference: Mechanobiology of Disease, 2016
✓ Mukherjee S., Maiti R. , Katiyar A. K., Das S. , Ray S. K., Novel Colloidal MoS2 Quantum Dot Heterojunctions on Silicon Platforms for Multifunctional Optoelectronic Devices, Scientific Reports, 2016
✓ Awasthi P., Mukherjee R. , Kare S. P., Das S., Impedimetric blood pH sensor based on MoS2 Nafion coated microelectrode, RSC Advances, 2016
✓ Kakati A., Maji D. , Das S., Unveiling Wet Chemical Etching Characteristics of Polydimethylsiloxane Film for Soft Micromachining Applications, Journal of Micromechanics and Microengineering, 27, 15033-15044, 2017
✓ Biswas S., Sikdar D. , Das D. , Mahadevappa M. , Das S., PDMS based multielectrode arrays for superior in-vitro retinal stimulation and recording, Biomedical microdevices, 2017
✓ Anura A., Das D. , Pal M. , Pal R. R., Das S. , Chatterjee J., Nanomechanical Signatures of Oral Submucous Fibrosis in Sub-epithelial Connective Tissue, Journal of the Mechanical Behavior of Biomedical Materials, 65, 705-715, 2017
✓ Wala J., Maji D. , Das S, Influence of physico-mechanical properties of elastomeric material for different cell growth, Biomedical Materials, 2017
✓ Biswas S., Das S. , Mahadevappa M., Design of electrode configuration for in vitro experiments of epiretinal electrical stimulation of retinal ganglion cell, , IET Science Measurement and Technology, 2017
✓ Maji D., Das S., Atomic force microscopy and nanoindentation investigation of polydimethylsiloxane elastomeric substrate compliancy for various sputtered thin film morphologies, J. Biomedical Materials Research Part A, 725-737, 2017
✓ Dey T., Mukherjee S. , Ghorai A. , Das S. , Ray S. K, Surface state selective tunable emission of graphene quantum dots exhibiting novel thermal quenching characteristics, Carbon, 394-403, 2018
✓ Parekh A., Das D. , Das S. , Dhara S. , Biswas K. , Mandal M. , Das S., Bioimpedimetric analysis in conjunction with growth dynamics to differentiate aggressiveness of cancer cells, Scientific Reports, 783-792, 2018
✓ Tripathi A. S., Chattopadhyay B. P., Das S., Cost-effective fabrication of ionic polymer based artificial muscles for catheter-guidewire maneuvering application, Microsystem Technologies, 25, 1129-1134, 2019

✓ Hybrid Nanostructures for Enhanced Photodetection & Other Optoelectronic Applications
✓ Solid State Dye Sanitized Solar Cells Using Hole Conductors, Polymers and Carbon Nanotube
✓ Nanotelectronics Network for Research and Application (NNetRA) - IIT Kharagpur
✓ Nano-electronics Network for Research and Application (NNetRA)- IIT Kharagpur (MEITY Part)
✓ Nano-electronics Network for Research and Applications (NNetRA)- IIT Kharagpur (DST Part)
✓ Bio-inspired Large Area Conformal and Flexible Sensors for Biomedical and Robotic Applications
✓ Nanotelectronics Network for Research and Application (NNetRA) - (IIT Kharagpur Part)
✓ Paper-based Point of Care Multiplex Bioanalytes Detection Device for Whole Blood Analysis (ICG_2017)

Ph.D

Two dimensional materials for devices