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gorachand

Gorachand Dutta

    Designation
    Assistant Professor Grade-1
  • Email
    g.dutta@smst.iitkgp.ac.in

Over the years, there are increasing needs for the development of simple, cost-effective, portable, integrated biosensors that can be operated outside the laboratory by untrained personnel. However, to reach this goal a reliable sensor technology based on printed electronics has to be developed. Our group aims to develop and establish the field of Biosensor and Electrochemistry for Bench to Bedside diagnosis. Our goal will be the use of redox cycling-based wash-free electrochemical technique in a portable electronic device that can be operated outside the laboratory for simple and effective point-or-care testing in India for early stage disease diagnosis (i.e. cancer, malaria, dengue, tuberculosis, HIV/AIDS etc.). The main challenges of point-of-care testing require to implement complex analytical methods into low-cost technologies. This is particularly true for countries with less developed health care infrastructure. Our washing-free technique is very simple and innovative. We can develop a low-cost disposable wash-free chip and our approach will make it possible to perform highly sensitive detection of biomarkers with printed electronics. The redox cycling technology will detect several interesting targets at the same time on a printed chip. The proposed research projects are inherently cross-disciplinary, combining expertise in biosensing, electrochemistry, electronics & electrical engineering, healthcare and manufacturing, entailing close collaboration and knowledge exchange among the different labs.
Also our focused areas: (1) integration of biosensors with fuel cell for self-powered biodevices, (2) low-cost, fully integrated biosensor devices using Lab-on-Printed Circuit Board (PCB) approach, (3) enzyme based immunosensor (ELISA), (4) ultra-sensitive biosensors using magnetic bead assays, nanoparticles, CNT, dendrimer, (5) Lab-on-a-Chip devices for biomedical diagnostics, (6) bio-nanotechnology for drug delivery, (7) microfluidics.

  • ✓ Dutta G., Yang H., Effect of fenton's reagent on the electrocatalytic activity of gold nanoparticles, Electrochemistry Communications, 13, 1328-1331, 2011
  • ✓ Dutta G., Debnath R. , Kalita A. , Kumar P. , Sarma M. , Shankar R. , Mondal B, An asymmetric dinuclear copper(II) complex with phenoxo and acetate bridges: Synthesis, structure and magnetic studies, Polyhedron, 30, 293-298, 2011
  • ✓ Dutta G., Jo K. , Lee H. , Kim B. , Woo H. , Yang H., Time-dependent decrease in the enhanced electrocatalytic activities observed after three different pretreatments of gold electrodes, Journal of Electroanalytical Chemistry, 675, 41-46, 2012
  • ✓ o K., Dutta G. , Kim J. , Yang ., Facile decrease in the electron-transfer rate and surface roughness of gold, Chemical Communication, 48, 8841-8843, 2014
  • ✓ Dutta G., Kim S. , Park S. , Yang H, Washing-free heterogeneous immunosensor using proximity-dependent electron mediation between an enzyme label and an electrode, Analytical Chemistry (ISSN: 0003-2700), 4589-4595, 2014
  • ✓ Dutta G., Haque A. , Yang H., Improvement of the electrocatalytic activities of long-aged Pt electrodes and the change of the improved activities with aging, Electrochimica Acta (ISSN: 0013-4686), 314, 319-323, 2014
  • ✓ Park S., Kim J. , Ock H. , Dutta G. , Shin E. , Yang H, Sensitive electrochemical detection of vaccinia virus in a solution containing a high concentration of L-ascorbic acid, Analyst (ISSN: 0003-2654), 140, 2015
  • ✓ Dutta G., Park S. , Singh A. , Seo J. , Kim S. , Yang H., Low-interference washing-free electrochemical immunosensor using glycerol-3-phosphate dehydrogenase as an enzyme label, Analytical Chemistry, 3574-3578, 2015
  • ✓ Dutta G., Yang H., Effects of Aging on Electrocatalytic Activities of Pt and Pd Nanoparticles, Journal of Electrochemical Science and Technology, 27-32, 2016
  • ✓ Dutta G., Nagarajan S. , Lapidus L. , Lillehoj P., Enzyme-free electrochemical immunosensor based on methylene blue and the electro-oxidation of hydrazine on Pt nanoparticles, Biosensors and Bioelectronics, 372-377, 2017
  • ✓ Dutta G., Lillehoj P., Wash-free, label-free immunoassay for rapid electrochemical detection of PfHRP2 in whole blood samples, Scientific Reports,, 2018
  • ✓ Dutta G., Regoutz A. , Moschou D., Commercially Fabricated Printed Circuit Board Sensing Electrodes for Biomarker Electrochemical Detection: The Importance of Electrode Surface Characteristics in Sensor Performance, Proceedings, (ISSN: 2504-3900), 2018
  • ✓ Dutta G., Jallow A. , Paul D. , Moschou D., Label-Free Electrochemical Detection of S. Mutans Exploiting Commercially Fabricated Printed Circuit Board Sensing Electrodes, Micromachines, 10, 2019
  • ✓ Dutta G., Electrochemical biosensors for rapid detection of malaria, Materials Science for Energy Technologies, 3, 150-158, 2020
  • ✓ Electrochemical Printed Chip Device for Next Generation Point-of-Care Disease Detection

Awards will be updated soon.

Patents will be updated soon.

Nirmita Dutta

Research Scholars

Ph.D

Biosensors for Point of care

Riddhipratim Mandal

Research Scholars

Ph.D

Biosensors

Srideep Maity

Research Scholars

Ph.D

Medical Image processing